Here, we demonstrated a critical role for IFN-γ/STAT1/STAT3 signaling in regulating PARP1 levels in HGSOC cells, in line with our recent results in cervical cancer [17], and with the emerging evidence on the functional interplay between the STATs signaling cascade and PARP1 [28,29,30,31]. This evidence concerns the gene IFNG and cervical cancer.