Indeed, enhanced TF activity was described for endothelial cells and a variety of cancer cell types upon treatment with several chemotherapeutic modalities, including cisplatin [16,17], doxorubicin [32] and gemcitabine [17,33], as well as increased TF expression levels on leukemia blood cells following treatment with L-asparaginase [34]. The gene discussed is TF; the disease is leukemia.