Tumor cells can secrete IL10, CXCL8, and TGFB1, which directly reduce NK cell cytotoxic functions [149,150,151] and/or recruit other immune cells such as Treg cells [152], MDSCs [153], CD11b + Ly6G + neutrophils [122,154], and DC [155], thus inhibiting NK cell functions indirectly. Here, IL10 is linked to neoplasm.