CTNNB1 and neoplasm: Overall, they were classified based on their immunosuppressive mechanism as follows: (1) CTNNB1 group (activation of Wnt/β-catenin signaling), (2) Treg group (regulatory T cell expression), (3) TAM group (tumor-associated macrophage M2 expression), and (4) high cytotoxicity group (high immune cytotoxicity but no immunosuppressive mechanisms).