TGFB1 and idiopathic pulmonary fibrosis: However, emerging studies seem to investigate its role in different disorders; for instance, the TGF-β1-induced EMT could provide the relevant quantity of fibroblasts in idiopathic pulmonary fibrosis (IPF), a chronic lung disease, characterized by morphologically abnormal alveolar epithelial cells (AEC), procoagulant factors and fibrogenic cytokines [53].