It was highlighted that HIV infection, in NSCLC patients, is associated with a poorer prognosis, and the loss of Tat-interacting protein 30 (TIP30) is related to metastasis via the promotion of TGF-β-induced EMT, invasion and stemness; the loss of TIP30 seemed to promote Snail nuclear translocation [58]. Here, HTATIP2 is linked to HIV infectious disease.