CD274 and soft tissue sarcoma: A meta-analysis by Zheng et al. [42], containing 15 studies and 1451 patients with bone and soft-tissue sarcoma, concluded that high expression levels of PDL1 were associated with poorer overall survival (HR 1.27, p < 0.001) and events-free survival (HR 2.05, p < 0.001), confirming the negative prognostic role of PDL1 expression.