A review by Thrift et al. also explores risk factors for developing gastric cancer from H. pylori infections, such as reduction in gastric acid secretion from oxyntic atrophy of the gastric fundus or body, and different carcinogenic potential based on various strains and virulence factors such as cytotoxin-associated-gene A (cagA) [22]. The gene discussed is S100A8; the disease is gastric cancer.