Furthermore, ICAM-1 and vascular cell adhesion molecule-1 (VCAM-1) expressed on the BE bind to lymphocyte function-associated antigen 1 (LFA-1, also known as integrin αLβ2) and very late antigen-4 (VLA-4, also known as integrin α4β1) expressed on tumor cells, respectively. The gene discussed is VCAM1; the disease is neoplasm.