SFRP1 and breast neoplasm: Interestingly, in the GENT2 platform [26], SFRP1 expression was higher in poorly differentiated breast tumors compared to moderately (log2 FC = 0.90; p-value < 0.05) and well-differentiated breast tumors (log2 FC = 2.49; p-value = 0.12; Figure S1A).