Hsa_circ_0045932 in CRC [66], as well as hsa_circ_0001806 and circ-PRMT5 in HCC [67,68], also accelerate glycolysis by upregulating HK2 expression through their ability to sponge miR-873-5p, miR-125b and miR-188-5p, respectively. The gene discussed is HK2; the disease is colorectal carcinoma.