NRP2 was characterized by skin cancer, several urothelial cancers, and a few lung cancers, showing moderate-to-strong cytoplasmic and/or membranous positivity; however, cervical cancers, along with several colorectal, gastric, pancreatic and liver cancers, showed moderate cytoplasmic and/or membranous immunoreactivity with additional nuclear membranous staining in several cases (Supplementary Figure S1B). This evidence concerns the gene NRP2 and skin cancer.