Lange et al. examined the combination of suberoylanilide hydroxamic acid and SBE13 for the treatment of HeLa cervical carcinoma cells and described strongly elevated cell numbers in G2/M and S phase, accompanied by decreasing G0/G1 percentages, polo-like kinase 1 (Plk1) protein reduction, p21 protein induction, as well as caspase-3 and poly (ADP-ribose) polymerase (PARP) activation [67]. Here, CASP3 is linked to cervical carcinoma.