PRKN and cervical carcinoma: Sun et al. described suberoylanilide hydroxamic acid to not only inhibit HDAC1/2/3, thereby promoting mitochondrial-dependent apoptosis but also involve the PTEN-induced putative kinase 1 (PINK1)-Parkin signaling pathway in human cervical cancer cell mitophagy induction in an acetylation-dependent manner [60], whereas Xia et al. found that vorinostat stimulates major histocompatibility class I related chain A (MICA) via the PI3K/Akt pathway and increases cervical cancer cell sensitivity to the natural killer cell-mediated cytolytic reactions [61].