Furthermore, most of the patients had more CD3+ (p = 0.006) and CD8+ (p = 0.004) T cells and tended to have more CD45RO+ T cells (p = 0.052) in the margins compared to IDC-P (Figure 3b), while the CD3+, CD8+ and CD45RO+ cell densities were less often decreased in IDC-P tissues compared to cancer or benign tissues (Figure 3a,c), resulting in a non-significant difference between the two compartments. This evidence concerns the gene CD8A and cancer.