CLEC9A and melanoma: In addition, the targeting of cDC1s, via a vector composed of the antigen coupled to a peptide with a high affinity for Clec9α (CBP-12; only 12 amino acids), makes it possible to induce a strong cytotoxic response in a mouse model of melanoma (responders or not to anti-PD-1) even in the absence of adjuvants [147].