M Ye et al. showed that overexpression of GLUT1 and MCT-4 led to a significant increase in glycolysis and autophagy in ER6 cells (erlotinib-resistant sub-line of HCC827) compared to EGFR-TKI sensitive HCC827 lung adenocarcinoma cell lines. The gene discussed is SLC2A1; the disease is lung adenocarcinoma.