Moreover, MLL-AF9-induced CD34+ cord blood cell signatures by Horton et al. [6], leukemic stem cells (LSCs) by Eppert et al. [35], signatures for cell cycle progression by Kanehisa et al. [36], and an AML signature by Köhler et al. [37] were enriched in our iMLL-AF9 cells (Figure 2D, right column). This evidence concerns the gene KMT2A and acute myeloid leukemia.