However, studies using CASK conditional KO mice done by Srivastava et al. and Patel et al. have shown that CASK deficiency does not significantly affect the migration or proliferation of CG cells [29,30], but progressive CG cell degeneration accounts for cerebellar hypoplasia in MICPCH syndrome. This evidence concerns the gene CASK and syndromic X-linked intellectual disability Najm type.