Furthermore, TRAP-, OC-STAMP- and Phospho-PKC-δ-positive cells were decreased by an anti-vimentin mAb injection compared with isotype-matched control mAb in the mouse periodontitis lesions, suggesting that OC-mediated bone resorption induced by a ligature attachment was suppressed by anti-vimentin mAb (Figure 5E). The gene discussed is ACP5; the disease is periodontitis.