RAG1 and rheumatoid arthritis: An anti-CV autoantibody isolated from human patients with rheumatoid arthritis was reported to induce OC-genesis in an ex vivo culture of human OC precursors derived from peripheral blood monocytes, whereas an anti-CV autoantibody was engaged in bone resorption in the tibia of Rag1-KO mice induced with rheumatoid arthritis [36,37].