Given the fact that VEGFA is involved in the response to ischemia and low output in patients with cardiopulmonary bypass (CPB) and in vascular adaptation to hemodynamic alterations, Kim et al. [62] investigated the effect of VEGF polymorphism on survival in 422 non-syndromic CHD children who underwent cardiac surgery before six months of life after cardiopulmonary bypass. Here, VEGFA is linked to coronary artery disorder.