A deletion of 10q26.13q26.3 region (8 Mb) containing the DOCK1 and C10ORF90 genes was an extremely rare chromosomal abnormality with less than 100 reported cases of DD, ID, dysmorphic facial features, and heart problems as well as skeletal and urogenital abnormalities [40]. Here, C10orf90 is linked to dentin dysplasia.