In this study, we performed comprehensive bioinformatics analysis on the expression pattern and clinical relationship between FAM210B in HCC patients from The Cancer Genome Atlas (TCGA) [15] to uncover the function of FAM210B in HCC. Moreover, we aimed to detect the role of cell growth and migration and comprehensively discussed the underlying process in vivo and in vitro. Here, MIMS2 is linked to hepatocellular carcinoma.