Multiple Yes-associated protein/TEA domain family member (YAP/TEAD)-regulated genes, including ZWILCH among other genes (AJUBA, ANLN, AREG, ARHGAP29, AURKA, BUB1, CCND1, CDK6, CXCL5, ED N2, DKK1, FOSL1, FOXM1, HBEGF, IGFBP2, JAG1, NOTCH2, RHAMM, RRM2, SERP1), have been linked to poor survival outcomes in individuals with pancreatic ductal adenocarcinoma [17]. The gene discussed is IGFBP2; the disease is pancreatic ductal adenocarcinoma.