The univariate analysis found for the whole cohort a significant association between DR and the following parameters: age increase of 1 year showed a 2% decrease (p = 0.002) in the odds ratio for DR; an increase of 11 mmol/mol HbA1c showed a 19% increase (p = 0.003) a 1-unit increase in the urine albumin-to-creatinine ratio showed a 1% increase (p = 0.008); a 1-unit increase in BMI showed a 6% decrease (p < 0.001); and a 1-year increase in DM duration showed a 13% increase (p < 0.001) in the odds ratio for DR. This evidence concerns the gene ALB and diabetic maculopathy.