VDR and obesity due to melanocortin 4 receptor deficiency: In this study we found no statistically significant differences in the percentage frequency distribution of all four VDR gene polymorphisms, Bsml, Taql, Apal and Fok1, among subjects with obesity, diabetes mellitus and hypertension compared to those without these conditions, except in the Fok1 AA genotype and G allele in subjects with diabetes and hypertension compared with those without these conditions.