Increases in D-dimer, a protein fragment produced during dissolution of blood clots, together with the pro-inflammatory marker, C-reactive protein (CRP), ferritin, TNF-α, IL-1β, IL-6, and IL-13, as well as sPLA2-IIA activity, were also found in patients with COVID-19 compared to normal persons [58]. This evidence concerns the gene CRP and COVID-19.