RARS1 and familial pancreatic carcinoma: In a zebrafish pancreatic cancer model, antagonization of RARs were used to downregulate miR-10a expression, resulting in a loss of invasive and metastatic phenotype; interestingly, it was also found that microRNA-10a (miR-10a) is an intermediate regulator between RARs and hox1 and hoxb3 [242].