In this way, at least five genes have been associated with this multigenic disease, including α-synuclein, leucine-rich repeat kinase 2 (LRRK2), parkin, phosphatase and tensin homolog-induced kinase 1 (PINK1), as well as DJ-1 [7], being promising therapeutic targets for the treatment of PD [8]. This evidence concerns the gene LRRK2 and Parkinson disease.