In regard to the suggested involvement of the inflammatory response in the development of NAFLD and T2DM, it was found that an increase in free radical-induced oxidation, TNF-α and NF-κB, and depletion of the antioxidant system appear to be the key factors in the development of NAFLD in patients with T2DM [152]. Here, TNF is linked to metabolic dysfunction-associated steatotic liver disease.