Recurrent CNAs in MYCN, 1q and 17p loci are considered good biomarkers for cancer monitoring through circulating tumor DNA (ctDNA) detection in liquid biopsy since they are reported in several pediatric malignancies [18,19,20,21,22,23,24] and can be identified using accessible methodologies, such as digital PCR (dPCR) and qPCR [25]. This evidence concerns the gene MYCN and cancer.