CDKN2A and posterior cortical atrophy: For example, McWilliams [63] studied 1143 patients with pancreatic adenocarcinoma and 1097 healthy controls, focusing on 28 genes known to be directly and indirectly involved in double-stranded break repair, as well as PRSS1, PRSS2, and CDKN2A, using a 768 SNP panel, and showed no significant association of any genes with altered PCa risk.