The plasma and the Mφs of the Asah1P361R/P361R Farber disease mouse model exhibited elevated levels of Cers, gangliosides, and their link to the higher levels of pro-inflammatory cytokines (e.g., IL1α, IL6, IL10, and IL12), chemokines (e.g., CCL2, CCL3, CCL12, CXCL1, CXCL9, and CXCL10), and the growth factor (e.g., VEGF) [176]. The gene discussed is CCL2; the disease is Farber lipogranulomatosis.