In order to explore the function of SNHG4 in the progression of endometrial cancer, siSNHG4 was transfected in both ECC1 and Ishikawa cells and knocked down, and the influence of the SNHG4 knock-down were inhibited assessed on the proliferation, migration, invasion, and metastasis of endometrial cancer cells. Here, SNHG4 is linked to endometrial cancer.