Importantly, fasting serum insulin levels and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) did not change significantly in the LDVD group but decreased significantly by 13 ± 8 μIU/mL in the HDVD group as did HOMA-IR, from 2.9 ± 0.2 to 1.8 ± 0.1. This evidence concerns the gene INS and Insulin resistance.