Our data demonstrate that patients with sarcoidosis showed no differences with the control group in relative numbers of CXCR5+ cells within CD45 RA+ CCR7+ “naïve” or thymus-divided Tregs, while they had an increased number of CXCR5+ Tregs in the CD45 RA–CCR7+ subset. Here, CXCR5 is linked to sarcoidosis.