APOE and atherosclerosis: As far as the NL are concerned, supplementation (10%, w/w) with refined OO in ApoE-deficient mice diet, in other words with only the NL OO fraction, resulted in more atherosclerotic lesions, while the enrichment of the above refined OO in linoleic, phytosterols, tocopherols, triterpenes, and waxes delayed the development of atherosclerosis [71].