METTL3 and nervous system disorder: Furthermore, in a retina-specific METTL3 conditional knockout mouse model [27], Xin et al. reported that the deletion of METTL3 promoted the degradation of retinal progenitor cell (RPC) transcripts and subsequently promoted the transition of RPCs into glial cells, indicating that a low level of METTL3 triggers glial cell formation, which is usually related to neurological disease pathogenesis [27].