Tao et al. demonstrated that downregulation of METTL3 enhanced the invasive properties of GBM by regulating the expression of cadherin 1(CDH1), cadherin 2(CDH2), matrix metallopeptidase 2(MMP2), and fibronectin 1(FN1) [59]. The gene discussed is METTL3; the disease is glioblastoma.