SNCA and Parkinson disease: Since the GBA1 pathogenic variants are the best described risk factors for Parkinson’s disease [5,31,32], we aimed to understand the molecular level relevance of the most commonly reported GBA1 variants, N370S and L444P, and performed the study on Lyso-Gb1 and α-synuclein as the most relevant markers of Gaucher and Parkinson’s disease, respectively.