A study of 796 SLE patients by Mehrani et al. showed that aβ2GPI IgM did not correlate with arterial or venous thrombosis but were protective against lupus nephritis (OR 0.54, p = 0.049) and hypertension (OR 0.58, p = 0.008) [37]. The gene discussed is CD40LG; the disease is systemic lupus erythematosus.