IGF1 and bronchopulmonary dysplasia: This profile mimics bronchopulmonary dysplasia in which pulmonary levels of IGF1 are upregulated while the circulating levels decline [38] and suggest that low levels of circulating IGF-1 might be merely markers of protein/muscle degradation, particularly that they were inversely correlated with oxygen saturation in one hand, and positively correlated with CRP levels in the other, in contrast to previous reports [39–41].