This study tests the hypothesis that altered miR-210-3p expression results in the development of endometriotic lesions by regulating IGFBP3 or COL8A1. We profiled the expression of our target genes in a baboon (Papio anubis) endometriosis model, in which the onset of endometriosis can be precisely determined [31], and in human samples. This evidence concerns the gene COL8A1 and endometriosis.