GPT and type 2 diabetes mellitus: Because liver fat accumulation has been reported to be associated with increased serum orosomucoid in addition to branched chain and aromatic amino acids19, and because orosomucoid and C-reactive protein (CRP) were associated with an increased risk of both type 2 diabetes and cardiovascular disease20, we also studied whether ALT/AST may be associated with serum orosomucoid.