Among 14 detected lipid glycosylation genes, phosphatidylinositol glycan anchor biosynthesis class M (PIGM) and UDP glycosyltransferase 8 (UGT8) increased in DLPFC and PHG of AD participants compared with controls (Fig. 5A,D, Supplementary Fig. S6A). This evidence concerns the gene UGT8 and Alzheimer disease.