While MET inhibition could be a means to radiosensitize MET-addicted tumors, since we have shown here that genetically preventing the DNA-PK-related phosphorylation of MET Serine 1016 radiosensitizes MET-addicted cancer cells, we hypothesize that this could be a rationale to study the use of DNA-PK inhibitors to radiosensitize MET-addicted tumors (selecting patients according to the phosphorylation status of MET Serine 1016 could support a refined stratification strategy). Here, MET is linked to cancer.