4/30 placental genes (TSTA3, BRD8, WDR82, SPG7) that were associated with both schizophrenia and bipolar disorder had opposite signs (Supplementary Data 47, 54), so they were predicted to be up-regulated in the placentae of individuals who developed one disorder and down-regulated in the other disorder. The gene discussed is BRD8; the disease is schizophrenia.