In parallel, we used targeted methylation sequencing to fine map obesity-associated DNA methylation changes in the regulatory regions flanking the sentinel sites at PRRC2A, LIMD2 and 69 additional loci (N = 43 subcutaneous and N = 46 visceral adipocyte samples, Supplementary Data 21). Here, LIMD2 is linked to obesity due to melanocortin 4 receptor deficiency.