We also identified potential causal effects of DNA methylation on central adiposity at 12 loci (10 subcutaneous, 2 visceral, measured using WHR), T2D at 4 loci (3 subcutaneous, 1 visceral), and fasting glucose, insulin and HbA1c at 3 loci (all subcutaneous, Fig. 4b, Supplementary Data 19). Here, INS is linked to type 2 diabetes mellitus.