Overall, ADSSL1 myopathy, Welander myopathy, myotilinopathy, MATR3 mutations associated with vocal cord and pharyngeal distal myopathy, filaminopathy, and MYOT-related myopathy appear to have a selective effect on parts of the hamstring muscles (semimembranosus and the long head of the biceps femoris muscles), while the anterior compartments are largely spared (24). The gene discussed is ADSS1; the disease is myopathy.