Our findings concur with those of McMurtry et al. (McMurtry et al., 2005), who showed increased survivin expression in pulmonary arteries of 6 patients with PAH and in the MCT-induced PH rat model, and with those of other models in vitro and in vivo exposed to hypoxia (Fan et al., 2015; Zhang et al., 2015; Zhang et al., 2016; Ye et al., 2022). This evidence concerns the gene BIRC5 and pulmonary arterial hypertension.