For intra-hepatic CCA model, markers including CK19, CK7, CK20, CEA, CDX2, CD15, CD133, CA19-9, MUC1, MUC2, S100P, TFF1, CD56, N-cadherin and EpCAM can be used to identify cancer type and cancer progression (97–104). Here, CDH2 is linked to cancer.