Subsequently, by analyzing the processed data corrected for batch effects, we found that the expression of GJB2 in LUAD tumor tissues (483 samples in TCGA) was higher than that in nonmalignant lung tissues (313 samples in GTEx, 59 samples in TCGA) (Figure 1B). In addition, for the same individual, the expression of GJB2 in the normal samples (pre-disease) and LUAD tissues (post-disease) was different. This evidence concerns the gene GJB2 and neoplasm.