After treatment of lung cancer cells, the expression of MMP-2 and MMP-9 was significantly reduced, the expression of mesenchymal markers Vimentin, N-cadherin, Slug, Snail, and MMP-9 was decreased, and the expression of epithelial marker E-cadherin was upregulated, indicating that ERIANIN inhibited the migration of lung cancer cells by inhibiting EMT (31). This evidence concerns the gene CDH2 and lung cancer.